Qotb Al-Din Al-Shirazi Muhammd Ibn Massud Ibn Muslih al-Farissi (1) was born in Shiraz, Iran in October 1236 (1,2). His family had a tradition of Sufism and his father, Zia al-Din Mas'ud Kazeruni was a leading Sufi of the order and also he was a physician by profession as the ophthalmologist (2,3). He practiced and taught medicine at the Mozaffari hospital in Shiraz. He died when Qotb al-Din was at the age of fourteen. Then Qotb al-Din trained and studied medicine under his uncle Kamal al-Din Abu'l Khayr (2,4). At the same time that Qotb al-Din lost his father, his uncle replaced him as the ophthalmologist at the Mozaffari hospital in Shiraz. Qotb al-Din also pursued his education under Sharaf al-Din Zaki Bushkani, and Shams al-Din Mohammad Kishi. These scientists and his uncle were expert teachers of the Qanun (the Canon), of Avicenna which is one of the most famous text books in medicine in Iran. When he became a student of Nasir al-Din Tussi (3) he studied the commentary on Canon written by Fakhr al-Din Razi (1). These two books led him to write his own commentary and resolved many of his issues (1-3)….